Non-invasive optical brain imaging

January 26, 2000
2:50 pm - 4:00 pm
Halligan 111
Speaker: Maria Angela Franceschini, Electro-Optics Technology Center, Tufts University


Near-infrared spectroscopy is an effective tool for the non-invasive monitoring of the cerebral hemodynamics and oxygenation. While it is well established that NIRS can reliably monitor changes in the cortical concentrations of oxy- and deoxy-hemoglobin, the absolute quantitation of the hemoglobin saturation is still an open question. I will present (1) spatially-resolved optical meaurements of oxy- and deoxy-hemoglobin concentrations changes during motor activation in human subjects, and (2) absolute cerebral saturation measurements on an animal model during hypoxia, hypercapnia, and hemodilution.