From cellular networks to biological functioning
Proteins accomplish virtually all of their cellular functions via interactions with other molecules. High-throughput experimental technologies, along with computational predictions, have resulted in large-scale protein interaction networks for numerous organisms. What can we learn about biological systems from these networks? I will discuss some of my group's efforts in understanding the relationship between simple network features and cellular functioning, and in developing interaction-based methods for uncovering proteins involved in human disease.
Mona Singh is a professor in the department of Computer Science and Lewis-Sigler Institute for Integrative Genomics at Princeton University. She received her BA from Harvard and her PhD from MIT. She received a Presidential Early Career Award for Scientists and Engineers (PECASE) in 2001. Her group develops algorithms for a diverse set of problems in computational molecular biology.